RESOURCES
A Multiscale Metabolic Model for Fed-batch Culture Process Control
Metalytics, Merck, MilliporeSigma, and University of Minnesota
Press & Projects
Presentations
Presentation to BioProcessing International 2020
Online Virtual Conference
September 21-25, 2020
Presentation to Bioprocessing Summit Europe 2021
Online Virtual Conference
March 16-17, 2021
Select Publications
Metabolic flux analysis has been utilized with a wide variety of organisms for a multitude of research, development and manufacturing applications, from cell line engineering and culture media optimization, to better understanding cancer cell biology and metabolic diseases. Below is a select list of publications from Metalytics’ Founder and Chief Scientific Officer, Dr. Jamey Young, a complete list of publications can be found here.
Application of 13C Flux Analysis to Identify High-Productivity CHO Metabolic Phenotypes
- Metabolic Engineering, 2017
13C Flux Analysis in Biotechnology and Medicine
- Systems Biology, 2017
Application of Isotope Labeling Experiments and 13C Flux Analysis to Enable Rational Pathway Engineering
- Current Opinion in Biotechnology, 2015
13C Metabolic Flux Analysis of Recombinant Expression Hosts
- Current Opinion in Biotechnology, 2014
The Impact of Anti-apoptotic Gene Bcl-2 Expression on CHO Central Metabolism
- Metabolic Engineering, 2014
Role of CHO Central Carbon Metabolism in Controlling the Quality of Secreted Biotherapeutic Proteins
- Pharmaceutical Bioprocessing, 2014
Metabolic Flux Rewiring in Mammalian Cell Cultures
- Current Opinion in Biotechnology, 2013
Peak Antibody Production is Associated with Increased Oxidative Metabolism in an Industrially Relevant Fed-batch CHO Cell Culture
- Biotechnology and Bioengineering, 2013
Oncogenic KRAS and BRAF Drive Metabolic Reprogramming in Colorectal Cancer
- Molecular and Cellular Proteomics, 2016
Mapping Cancer Cell Metabolism with 13C Flux Analysis: Recent Progress and Future Challenges
- Journal of Carcinogenesis, 2013
Mass Spectrometry-based Microassay of 2H and 13C Plasma Glucose Labeling to Quantify Liver Metabolic Fluxes in vivo
- American Journal of Physiology, 2015
Tracking Cellular Metabolomics in Lipoapoptosis- and Steatosis-developing Liver Cells
- Molecular BioSystems, 2011
Events
Bioprocessing Summit Europe
March 16-17, 2021
Virtual Online Conference
BIO International Convention
June 10-18, 2021
Virtual Online Conference
BioProcess International - US West
March 29-31, 2021
Virtual Online Conference
Bioprocessing Summit
August 16-19, 2021
Sheraton Boston (MA) & Online