RESOURCES
PRESS RELEASE
Metalytics is pleased to announce a new collaboration with Merck KGaA, Darmstadt, Germany. For over half a decade, we have worked closely with MilliporeSigma, the Life Science business of Merck. This new partnership strengthens that relationship and enables the organization to further leverage our CoreMFA™ technology to advance CHO media development.
By combining CoreMFA Metabolic Flux Analysis with MilliporeSigma’s statistical and rational design tools, Millipore Sigma is able to design a custom media which is unique to their customers cell line. This custom media enhances overall productivity and improves cell robustness, with MFA offering unique advantages that can accelerate project timelines and help identify previously undetected bottlenecks.
Research Triangle Park, NC
December 10, 2025
Press & Projects
Presentations
Poster Presentation at 2022 ACS Spring Meeting
San Diego, CA, and Online; March 20-24, 2022
click on image above for link to full poster presentation
Poster Presentation at NIIMBL 2021 Annual Meeting
Washington, DC, and Online; July 14-16, 2021
click on image above for link to full poster presentation
Presentation to Bioprocessing Summit Europe 2021
Online Conference; March 16-17, 2021
click on image above for narrated presentation
Presentation to BioProcessing International 2020
Online Conference; September 21-25, 2020
click on image above for narrated presentation
PRESS RELEASE
In this work, Metalytics used Metabolic Flux Analysis (MFA) to determine how branched-chain keto acid supplementation reshaped Merck Life Sciences (MLS)’s CHO cell metabolism and to identify the metabolic changes associated with improved cell productivity, including unexpected shifts in central carbon flux and cellular energy metabolism. This helped explain how specific media formulation changes can directly influence antibody production and provided support for this strategy as a process optimization approach.
Research Triangle Park, NC
February 16, 2026
Select Publications
Metabolic flux analysis has been utilized with a wide variety of organisms for a multitude of research, development and manufacturing applications, from cell line engineering and culture media optimization, to better understanding cancer cell biology and metabolic diseases. Below is a select list of publications from Metalytics’ Founder and Chief Scientific Officer, Dr. Jamey Young, a complete list of publications can be found here.