VISUALIZING METABOLISM, PROVIDING ACTIONABLE RESULTS

Metalytics specializes in mapping metabolic reaction rates in a wide variety of cell lines used to produce a myriad of products across various life science industries. We are committed to delivering unparalleled metabolic flux analysis and providing actionable results that will accelerate our client’s research, development, and manufacturing goals.

BEYOND METABOLOMICS

Traditional metabolomics studies are useful, but they are a static list of metabolites, a snapshot in time. If metabolomics can be considered a road map, metabolic flux analysis (MFA) is real-time traffic flow, identifying bottlenecks that constrain cellular growth and productivity. Our CoreMFA platform is dynamic, comprehensive, and quantitative - providing actionable results and enabling further scenario analyses. Metabolomics can help you generate hypotheses, CoreMFA allows you to test  those hypotheses and make tangible, significant process improvements.

 

WHAT WE DO

Metabolic flux analysis mathematically models metabolic pathways and pinpoints nodes and bottlenecks that constrain cellular growth and production.  Genetic engineering techniques and/or culture media optimization can then be used to modify the pathway in order to relieve these constraints.  By using our CoreMFA platform, companies can drastically reduce analysis complexity, accelerate their understanding of the metabolic processes involved in their cell factories, and more quickly and rationally improve both the quality and quantity of end products.

We Give You a Competitive Advantage

  • Increased production capacity & efficiency

  • Engineered cell lines

  • Optimized culture media

  • Reduced raw material costs

  • Accelerated time to market

  • Increased ROI and profitability

 

We Optimize and Accelerate Your Bioprocessing Research, Development, and Manufacturing

  • Modeling metabolic reaction rates in cell factories

  • Deploying metabolic flux analysis with advanced, proprietary software systems

  • Accelerating R&D and process improvements

  • Improving efficiency and productivity

  • Solving complex production issues

We explore your challenges, identify desired outcomes, and develop a plan of action.

You simply send us your samples. We'll generate flux data and maps, provide data analysis and

interpretation, and produce actionable results that will inform and prioritize your next steps.

We provide detailed protocols customized to your cell line and culture conditions.

“We use yeast and E.coli to manufacture commodities and specialty chemicals. We wanted to know the metabolic flux and tried 7 different approaches, but Metalytics’ technology was the best thing for understanding what was going on.” - Dr. Joshua Lerman, Amyris

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